Agile SciTech
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Subvisible particle analysis

Light obscuration tells you how many particles there are. Flow imaging shows you what they are — protein aggregates, silicone oil, air bubbles or foreign matter — so you can find the root cause.

Who uses it

QC labs testing parenterals, formulation teams, and cell and gene therapy developers.

Partners in this workflow
FlowCamUnchained Labs

Challenges we help solve

Challenge 1Counts without causes

Light obscuration alone cannot tell protein aggregates from silicone oil droplets.

Challenge 2Translucent protein particles

Low-contrast aggregates are under-counted by traditional methods.

Challenge 3Investigating out-of-spec results

Root-cause work needs images and morphology data, fast.

The workflow, step by step

  1. 1Early aggregation check

    Detect nanometre-to-micron aggregates with light scattering.

    Unchained Stunner, Aunty
  2. 2Image & count

    Capture every particle in the subvisible range.

    FlowCam 8000 · FlowCam Nano
  3. 3Compendial comparison

    Run imaging alongside light obscuration in one instrument.

    FlowCam LO
  4. 4Classify & report

    Sort particles by type and build a library.

    VisualSpreadsheet® software

Recommended products

6 products for this workflow. Click a picture for a quick view, or add products to your quote list.

Quote the whole workflow

Tell us your product type and particle size range.

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