Cell & gene therapy (AAV, lentivirus, LNP)
Six partners, one workflow: GMP reagents and media for production, nanoparticle formulation, and the analytics to measure titre, particle quality and purity.
Gene therapy and mRNA developers, CAR-T and cell therapy teams, viral vector CDMOs and academic translational centres.
Challenges we help solve
Genome titre by qPCR varies with standard curves; regulators expect robust quantification.
Empty and partial capsids reduce potency and must be measured lot to lot.
Cytokines, growth factors and supplements need documentation fit for clinical manufacturing.
The workflow, step by step
- 1Production inputs
GMP proteins for cell expansion; supplements for vector yield.
Bio-Techne GMP proteins · CELLiST AAV supplement - 2Formulation
Encapsulate nucleic acids in LNPs at screening to GMP scale.
Unchained Sun-series · Inscinstech assembly - 3Titre & copy number
Absolute genome titre, residual DNA, vector copy number.
RainSure RS32 · DropDx dPCR - 4Particle quality
Size, concentration, full/empty and single-particle data.
Unchained Stunner AF · Leprechaun - 5Purity & identity
Protein identity and purity of vectors and products.
Bio-Techne Simple Western, Maurice
Recommended products
9 products for this workflow. Click a picture for a quick view, or add products to your quote list.